Our Pipeline
A Pipeline of Novel Immunotherapy Treatments
Dispatch is advancing a first-of-its-kind pipeline of novel immunotherapy programs for solid tumors, which represent ~90% of all cancers and have been challenging to address with immunotherapy treatments. By combining the strengths of immunotherapy with a tumor-specific virus, both engineered to clear tumor cells with precision and power, we are leveraging our Flare platform to help create a world where all patients with cancer can be cured.
Our platform dispatches a tumor-specific virus equipped with a novel universal antigen — Flare — that tags solid tumor cells with exquisite specificity while activating the immune system and remodeling the tumor microenvironment. The Flare antigen acts as a beacon, guiding the immune system to find and clear marked cancer cells while avoiding healthy tissue.
Both of Dispatch’s initial programs, DISP-10 and DISP-11, leverage the Flare platform in combination with approved immunotherapy treatments.
| Program | Technologies | Indications | Drug Discovery | Preclinical | Phase 1 | Phase 2/3 | |
|---|---|---|---|---|---|---|---|
DISP-10 | DV-10 + ide-cel CAR T | GI cancers | Enrolling | ||||
DISP-11 | DV-10 + zevor-cel CAR T | GI cancers | |||||
DISP-14 | Undisclosed | Solid tumors of epithelial origin | |||||
DISP-40 | Undisclosed | Solid tumors of epithelial origin | |||||
DISP-44 | Undisclosed | Solid tumors of epithelial origin | |||||
DISP-10Phase 1 -Enrolling TechnologiesDV-10 + ide-cel CAR T IndicationsGI cancers | |||
DISP-11Preclinical TechnologiesDV-10 + zevor-cel CAR T IndicationsGI cancers | |||
DISP-14Preclinical TechnologiesUndisclosed IndicationsSolid tumors of epithelial origin | |||
DISP-40Preclinical TechnologiesUndisclosed IndicationsSolid tumors of epithelial origin | |||
DISP-44Preclinical TechnologiesUndisclosed IndicationsSolid tumors of epithelial origin |
Abbreviations: BCMA, B- cell maturation antigen; CAR, chimeric antigen receptor; CXCL9, C-X-C motif chemokine ligand 9; DV, Dispatch virus ; IL-18, interleukin-18; IND, investigational new drug.

